Journal Articles (Google scholar)
# Undergraduate student, $ Graduate student, @ Visiting student
63. Yang Z and Xu P*. (2021). Implementing CRISPR-Cas12a for Efficient Genome Editing in Yarrowia lipolytica. Methods in Molecular Biology, In press.
62. Sun W, Yang Z and Xu P*. (2021). Engineering Yarrowia lipolytica for Production of Fatty Alcohols with YaliBrick Vectors. Methods in Molecular Biology. In Press.
61. Tong Y, Zhou J, Zhang L and Xu P*. (2021). A Golden-Gate based cloning toolkit to build violacein pathway libraries in Yarrowia lipolytica. ACS Synthetic Biology, 10(1): 115-124.
60. Gu Y and Xu P*. (2021) Synthetic yeast brews neuroactive compounds. Nature Chemical Biology. 17: 8-9.
59. Tang L, Xu P and Zhang H. (2020) Editorial overview in tissue, cell and pathway engineering: programming biology for smart therapeutics, microbial cell factory and intelligent biomanufacturing. Current opinion in Biotechnology. 66: ii-vi.
58. Ma J, Gu Y and Xu P*. (2020) A roadmap to engineering antiviral natural products synthesis in microbes. Current opinion in Biotechnology. 66: 140-149.
57. Liu Y, Li J, Ledesma-Amaro R, Xu P, Du G and Liu L*. (2020) Towards next generation model microorganism chassis for biomanufacturing. Applied Microbiology and Biotechnology. 104: 9095–9108.
56. Edwards H and Xu P* (2020). Unstructured kinetic models to simulate an arabinose switch that decouples cell growth from metabolite production. Synthetic & Systems Biotechnology, 5(3):222-229.
55. Ma J, Gu Y and Xu P*. (2020) Synthetic biology, systems biology and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform. Journal of Industrial Microbiology & Biotechnology. 47(9): 845-862.
54. Qiu X, Xu P, et al, Zhang J and Li J. (2020) Combining genetically-encoded biosensors with high throughput strain screening to maximize erythritol production in Yarrowia lipolytica. Metabolic Engineering, 60, 66-76.
53. Xu P*. (2020) Applying chemical reaction transition theory to predict the latent transmission dynamics of coronavirus outbreak in China. Under review.
52. Xu P*. (2021) Dynamics of microbial competition, commensalism and cooperation and its implications for coculture and microbiome engineering. Biotechnology and Bioengineering. 118(1):199-209.
51. Liu H, Wang F, Deng L and Xu P*. (2020). Genetic and bioprocess engineering to improve squalene production in Yarrowia lipolytica. Bioresource Technology, 317: 123991.
50. Gu Y, Ma J, Lv Y, et al and Xu P*.(2020) Engineering Yarrowia lipolytica as a chassis for de novo synthesis of five aromatic-derived natural products and chemicals. ACS Synthetic Biology. 9(8): 2096-2106.
49. Marsafari M, Ma J, Koffas M and Xu P*. (2020) Genetically encoded biosensors for analyzing and controlling cellular process in yeast. Current Opinion in Biotechnology. 64, 175-182.
48. Lv Y, Gu Y, Xu J, Zhou J and Xu P*. (2020) Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield. Metabolic Engineering, 61, 79-88.
47. Marsafari M, Samizadeh H, Rabiei B, Mehrabi A, Koffas* M and Xu P*. (2020). Biotechnological production of flavonoids: an update on plant metabolic engineering, microbial host selection and genetically encoded biosensors. Biotechnology Journal. 15(8): 1900432.
46. Gu Y, Ma J, Zhu Y, Liu L and Xu P* (2020). Refactoring Ehrlich pathway for high-yield 2-phenylethanol production in Yarrowia lipolytica. ACS Synthetic Biology, 9 (3), 623-633.
45. Xu P*, Masarfari M, et al and Koffas MA. (2020) Microbial coculture for flavonoid synthesis. Trends in Biotechnology, 38(7): 686-688.
44. Edwards H, Yang Z, and Xu P* (2020). Characterization of Met25 as a Color Associated Genetic Marker in Yarrowia lipolytica. Metabolic Engineering Communications. 11: e00147.
43. Marsafari M and Xu P*. (2020). Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica. Metabolic Engineering Communications. 10: e00121.
42. Xu P* (2020). Branch point control at malonyl-CoA node: A computational framework to optimize the controller architecture toward ideal metabolic switches. Metabolic Engineering Communications. 10: e00127.
41. Xu P* (2020). Analytical solution for a hybrid Logistic-Monod cell growth model in batch and CSTR culture. Biotechnology and Bioengineering. 117: 873-878.
40. Yang Z, Edwards H and Xu P* (2019). CRISPR-Cas12a/Cpf1-assisted precise, efficient and multiplexed genome-editing in Yarrowia lipolytica. Metabolic Engineering Communications. 10: e00112
39. Gao C, Xu P, Ye C, Chen X and Liu L. (2019) Genetic Circuit-Assisted Smart Microbial Engineering. Trends in Microbiology. 27(12): 1011-1024.
38. Gao C, Dr. Hou J, Xu P, Guo L, Chen X, Hu G, Ye C, Edwards H, Chen J, Chen W and Liu L. (2019). Programmable biomolecular switches for rewiring flux in Escherichia coli. Nature Communications, 10 (1), 1-12.
37. Lv Y et al Xu P*. (2019) Optimizing oleaginous yeast cell factories for flavonoids and hydroxylated flavonoids biosynthesis. ACS Synthetic Biology. 8(11), 2514-2523.
36. Liu H, Marsafari M et al Xu P*. (2019) Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica. Metabolic engineering 56, 60-68.
35. Lv Y($), Qian S, Du G, Chen J, Zhou J and Xu P*. (2019) Coupling feedback genetic circuits with growth phenotype for dynamic population control and intelligent bioproduction. Metabolic engineering. 54, 109-116.
34. Wan X, Marsafari M($) and Xu P*. (2019). Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives. Microbial cell factories. 18 (1), 61
33. Lv Y($), Edwards H($), Zhou J and Xu P*. (2019) Combining 26s rDNA and the Cre-loxP system for iterative gene integration and efficient marker curation in Yarrowia lipolytica. ACS Synthetic Biology. 8 (3), 568-576.
32. Liu H($), Marsafari M($), Deng L and Xu P*. (2019) Understanding lipogenesis by dynamically profiling transcriptional activity of lipogenic promoters in Yarrowia lipolytica. Applied Microbiology and Biotechnology. 103 (7), 3167-3179.
31. Aris H(#), Borhani S(#), Cahn D(#), O'Donnell C(#), Tan E(#), Xu P*. (2019) Modeling transcriptional factor cross-talk to understand parabolic kinetics, bimodal gene expression and retroactivity in biosensor design. Biochemical Engineering Journal. 144, 209-216.
30. Hu G, Zhou J, Chen X, Qian Y, Gao C, Guo L, Xu P, Chen W, Chen J, Li Y, Liu L (2018) Engineering synergetic CO2-fixing pathways for malate production. Metabolic engineering 47, 496-504
29. Gao C, Wang S, Hu GP, Guo L, Chen X, Xu P and Liu L. (2018) Engineering Escherichia coli for malate production by integrating modular pathway characterization with CRISPRi-guided multiplexed metabolic tuning. Biotechnology and Bioengineering. 115 (3), 661-672
28. Xu P. Production of chemicals using dynamic control of metabolic fluxes. (2018) Current Opinion in Biotechnology, 53, 12-19
27. Johnson AO, Gonzalez-Villanueva M, Wong L($), Steinbüchel A, Tee KL, Xu P, Wong TS. (2017) Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories, Metabolic Engineering, 44:253-264. Link
26. Jin Eq(@), Engel J(#) and Xu P. (2017) Rapid evolution of regulatory element libraries for tunable transcriptional and translational control of gene expression. Synthetic and Systems Biotechnology, 2 (4), 295-301
25. Wong L($). Engel J(#), Jin EQ(@), Holdridge B(#) and Xu P. (2017) YaliBricks, a versatile genetic toolkit for streamlined and rapid pathway engineering in Yarrowia lipolytica. Metabolic Engineering Communications, 5: 68-77. Link
24. Wong L($), Holdridge B(#), Engel J(#) and Xu P. (2019) Genetic tools for streamlined and accelerated pathway engineering in Yarrowia lipolytica. Methods in Molecular Biology: Microbial Metabolic Engineering. 155-177.
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Before Joining UMBC
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23. Xu P, Qiao K and Stephanopoulos G. (2016) Engineering redox homeostasis and aldehyde detoxification to improve lipid production in Yarrowia lipolytica. Biotechnology and Bioengineering, 114 (7), 1521-1530
22. Qiao K, Wasylenko T, Zhou K, Xu P and Stephanopoulos G. (2017) Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism. Nature Biotechnology, 35 (2), 173-177 MIT news.
21. Xu P, Qiao K, Ahn WK and Stephanopoulos G. (2016) Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals. Proceedings of the National Academy of Sciences, U.S.A., 113 (39), 10848-10853. Highlighted by Nature and Highlighted by DOE Office of Science.
20. Xu P, Rizzoni EA, Sul SY and Stephanopoulos G. (2016) Improving metabolic pathway efficiency by statistical model based multivariate regulatory metabolic engineering. ACS Synthetic Biology, 6 (1), 148-158.
19. Silverman, A, Qiao K, Xu P and Stephanopoulos GN. (2015) Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica. Applied Microbiology and Biotechnology. 100(8):3781-98. Link
18. Lim CG, Wong L, Bhan N, Dvora H, Xu P, Koffas M. (2015) Development of a recombinant Escherichia coli strain for overproduction of the plant pigment anthocyanin. Applied and Environmental Microbiology. 81(18):6276-84. Link
17. Trantas EA, Koffas MA, Xu P and Ververidis F. (2015) Biotechnology of flavonoids: Metabolic engineering with commercial applications when plants produce not enough or at all. Frontiers in Plant Science, 6:7.
16. Bhan N, Li L, Cai C, Xu P, Linhardt R and Koffas M. (2015) Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase. Protein Science, 24: 167-173.
15. Xu P, Li L, Zhang F, Stephanopoulos GN and Koffas MA. (2014) Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proceedings of the National Academy of Sciences, U.S.A., 111(31):11299-304. Highlighted as cover article on RPI news release.
14. Xu P, Wang W, Li L, Bhan N, Zhang F and Koffas MA. (2014) Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in E. coli. ACS Chemical Biology, 9(2): 451-458.
13. Wang W, Englaender J, Xu P, Linhardt RJ, Koffas MA. (2013) Expression of low endotoxin 3-O-sulfotransferase in B. subtilis and B. megaterium. Applied Biochemistry and Biotechnology, 171(4): 954-962.
12. Xu P, Gu Q; Wang W, Wong L, Bower A, Collins CH and Koffas MA. (2013) Modular optimization of multi-gene pathway for fatty acids production in E. coli. Nature Communications, 4: 1409.
11. Xu P, Bhan N and Koffas MA. (2013) Engineering plant metabolism into microbes: from systems biology to synthetic biology. Current Opinion in Biotechnology. 24(2): 291-299.
10. Bhan N, Xu P and Koffas MA. (2013) Pathway and protein engineering approaches to produce novel and commodity small molecules. Current Opinion in Biotechnology, 24(6): 1137-1143.
9. Bhan N, Xu P, Khalidi O and Koffas MA. (2013) Redirecting carbon flux into Malonyl-CoA to improve Resveratrol titers: Proof of concept for genetic interventions predicted by OptForce computational framework. Chemical Engineering Science, 103: 109-114.
8. Xu P and Koffas MA. (2013) Assembly of multi-gene pathways and combinatorial pathway libraries through ePathBrick vectors. Methods in Molecular Biology: Synthetic Biology. 1073:107-29.
7. Xu P, Vansiri A, Bhan N and Koffas MA. (2012) ePathBrick: A synthetic biology platform for engineering metabolic pathways in E. coli. ACS Synthetic Biology, 1(7):256–266.
6. Xu P, Ranganathan S, Fowler Z, Maranas CD and Koffas MA. (2011) Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. Metabolic Engineering, 13(5): 578-587.
5. Zhang L, Ding Z, Xu P et al. (2011) Methyl lucidenate F isolated from the ethanol-soluble-acidic components of G. lucidum is a novel tyrosinase inhibitor. Biotechnology and Bioprocess Engineering, 16(3): 457-461.
4. Xu P and Koffas MA. (2010) Metabolic engineering of E. coli for biofuel production, Biofuels, 1(3): 493-504.
3. Zhang T, Xu P et al. (2009) Identification of biological wort turbidity caused by microbial contamination of Gairdner barley. Journal of the American Society of Brewing Chemists, 67(1): 33-37.
2. Xu P, Ding Z, Qian Z, Zhang K and Zhao C. (2008) Improved production of mycelial biomass and ganoderic acid by submerged culture of G. lucidum SB97 using complex media. Enzyme and Microbial Technology, 42(4): 325-331.
1. Xu P, Qian Z, Zhao CX. (2008) Kinetic analysis of exo-polysaccharide and ganoderic acid production by submerged culture of Ganoderma lucidum. Chinese Journal of Applied & Environmental Biology, 14(4): 562-565. 1. Xu P*.
# Undergraduate student, $ Graduate student, @ Visiting student
63. Yang Z and Xu P*. (2021). Implementing CRISPR-Cas12a for Efficient Genome Editing in Yarrowia lipolytica. Methods in Molecular Biology, In press.
62. Sun W, Yang Z and Xu P*. (2021). Engineering Yarrowia lipolytica for Production of Fatty Alcohols with YaliBrick Vectors. Methods in Molecular Biology. In Press.
61. Tong Y, Zhou J, Zhang L and Xu P*. (2021). A Golden-Gate based cloning toolkit to build violacein pathway libraries in Yarrowia lipolytica. ACS Synthetic Biology, 10(1): 115-124.
60. Gu Y and Xu P*. (2021) Synthetic yeast brews neuroactive compounds. Nature Chemical Biology. 17: 8-9.
59. Tang L, Xu P and Zhang H. (2020) Editorial overview in tissue, cell and pathway engineering: programming biology for smart therapeutics, microbial cell factory and intelligent biomanufacturing. Current opinion in Biotechnology. 66: ii-vi.
58. Ma J, Gu Y and Xu P*. (2020) A roadmap to engineering antiviral natural products synthesis in microbes. Current opinion in Biotechnology. 66: 140-149.
57. Liu Y, Li J, Ledesma-Amaro R, Xu P, Du G and Liu L*. (2020) Towards next generation model microorganism chassis for biomanufacturing. Applied Microbiology and Biotechnology. 104: 9095–9108.
56. Edwards H and Xu P* (2020). Unstructured kinetic models to simulate an arabinose switch that decouples cell growth from metabolite production. Synthetic & Systems Biotechnology, 5(3):222-229.
55. Ma J, Gu Y and Xu P*. (2020) Synthetic biology, systems biology and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform. Journal of Industrial Microbiology & Biotechnology. 47(9): 845-862.
54. Qiu X, Xu P, et al, Zhang J and Li J. (2020) Combining genetically-encoded biosensors with high throughput strain screening to maximize erythritol production in Yarrowia lipolytica. Metabolic Engineering, 60, 66-76.
53. Xu P*. (2020) Applying chemical reaction transition theory to predict the latent transmission dynamics of coronavirus outbreak in China. Under review.
52. Xu P*. (2021) Dynamics of microbial competition, commensalism and cooperation and its implications for coculture and microbiome engineering. Biotechnology and Bioengineering. 118(1):199-209.
51. Liu H, Wang F, Deng L and Xu P*. (2020). Genetic and bioprocess engineering to improve squalene production in Yarrowia lipolytica. Bioresource Technology, 317: 123991.
50. Gu Y, Ma J, Lv Y, et al and Xu P*.(2020) Engineering Yarrowia lipolytica as a chassis for de novo synthesis of five aromatic-derived natural products and chemicals. ACS Synthetic Biology. 9(8): 2096-2106.
49. Marsafari M, Ma J, Koffas M and Xu P*. (2020) Genetically encoded biosensors for analyzing and controlling cellular process in yeast. Current Opinion in Biotechnology. 64, 175-182.
48. Lv Y, Gu Y, Xu J, Zhou J and Xu P*. (2020) Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield. Metabolic Engineering, 61, 79-88.
47. Marsafari M, Samizadeh H, Rabiei B, Mehrabi A, Koffas* M and Xu P*. (2020). Biotechnological production of flavonoids: an update on plant metabolic engineering, microbial host selection and genetically encoded biosensors. Biotechnology Journal. 15(8): 1900432.
46. Gu Y, Ma J, Zhu Y, Liu L and Xu P* (2020). Refactoring Ehrlich pathway for high-yield 2-phenylethanol production in Yarrowia lipolytica. ACS Synthetic Biology, 9 (3), 623-633.
45. Xu P*, Masarfari M, et al and Koffas MA. (2020) Microbial coculture for flavonoid synthesis. Trends in Biotechnology, 38(7): 686-688.
44. Edwards H, Yang Z, and Xu P* (2020). Characterization of Met25 as a Color Associated Genetic Marker in Yarrowia lipolytica. Metabolic Engineering Communications. 11: e00147.
43. Marsafari M and Xu P*. (2020). Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica. Metabolic Engineering Communications. 10: e00121.
42. Xu P* (2020). Branch point control at malonyl-CoA node: A computational framework to optimize the controller architecture toward ideal metabolic switches. Metabolic Engineering Communications. 10: e00127.
41. Xu P* (2020). Analytical solution for a hybrid Logistic-Monod cell growth model in batch and CSTR culture. Biotechnology and Bioengineering. 117: 873-878.
40. Yang Z, Edwards H and Xu P* (2019). CRISPR-Cas12a/Cpf1-assisted precise, efficient and multiplexed genome-editing in Yarrowia lipolytica. Metabolic Engineering Communications. 10: e00112
39. Gao C, Xu P, Ye C, Chen X and Liu L. (2019) Genetic Circuit-Assisted Smart Microbial Engineering. Trends in Microbiology. 27(12): 1011-1024.
38. Gao C, Dr. Hou J, Xu P, Guo L, Chen X, Hu G, Ye C, Edwards H, Chen J, Chen W and Liu L. (2019). Programmable biomolecular switches for rewiring flux in Escherichia coli. Nature Communications, 10 (1), 1-12.
37. Lv Y et al Xu P*. (2019) Optimizing oleaginous yeast cell factories for flavonoids and hydroxylated flavonoids biosynthesis. ACS Synthetic Biology. 8(11), 2514-2523.
36. Liu H, Marsafari M et al Xu P*. (2019) Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica. Metabolic engineering 56, 60-68.
35. Lv Y($), Qian S, Du G, Chen J, Zhou J and Xu P*. (2019) Coupling feedback genetic circuits with growth phenotype for dynamic population control and intelligent bioproduction. Metabolic engineering. 54, 109-116.
34. Wan X, Marsafari M($) and Xu P*. (2019). Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives. Microbial cell factories. 18 (1), 61
33. Lv Y($), Edwards H($), Zhou J and Xu P*. (2019) Combining 26s rDNA and the Cre-loxP system for iterative gene integration and efficient marker curation in Yarrowia lipolytica. ACS Synthetic Biology. 8 (3), 568-576.
32. Liu H($), Marsafari M($), Deng L and Xu P*. (2019) Understanding lipogenesis by dynamically profiling transcriptional activity of lipogenic promoters in Yarrowia lipolytica. Applied Microbiology and Biotechnology. 103 (7), 3167-3179.
31. Aris H(#), Borhani S(#), Cahn D(#), O'Donnell C(#), Tan E(#), Xu P*. (2019) Modeling transcriptional factor cross-talk to understand parabolic kinetics, bimodal gene expression and retroactivity in biosensor design. Biochemical Engineering Journal. 144, 209-216.
30. Hu G, Zhou J, Chen X, Qian Y, Gao C, Guo L, Xu P, Chen W, Chen J, Li Y, Liu L (2018) Engineering synergetic CO2-fixing pathways for malate production. Metabolic engineering 47, 496-504
29. Gao C, Wang S, Hu GP, Guo L, Chen X, Xu P and Liu L. (2018) Engineering Escherichia coli for malate production by integrating modular pathway characterization with CRISPRi-guided multiplexed metabolic tuning. Biotechnology and Bioengineering. 115 (3), 661-672
28. Xu P. Production of chemicals using dynamic control of metabolic fluxes. (2018) Current Opinion in Biotechnology, 53, 12-19
27. Johnson AO, Gonzalez-Villanueva M, Wong L($), Steinbüchel A, Tee KL, Xu P, Wong TS. (2017) Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories, Metabolic Engineering, 44:253-264. Link
26. Jin Eq(@), Engel J(#) and Xu P. (2017) Rapid evolution of regulatory element libraries for tunable transcriptional and translational control of gene expression. Synthetic and Systems Biotechnology, 2 (4), 295-301
25. Wong L($). Engel J(#), Jin EQ(@), Holdridge B(#) and Xu P. (2017) YaliBricks, a versatile genetic toolkit for streamlined and rapid pathway engineering in Yarrowia lipolytica. Metabolic Engineering Communications, 5: 68-77. Link
24. Wong L($), Holdridge B(#), Engel J(#) and Xu P. (2019) Genetic tools for streamlined and accelerated pathway engineering in Yarrowia lipolytica. Methods in Molecular Biology: Microbial Metabolic Engineering. 155-177.
%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%
Before Joining UMBC
%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%%@@@@%
23. Xu P, Qiao K and Stephanopoulos G. (2016) Engineering redox homeostasis and aldehyde detoxification to improve lipid production in Yarrowia lipolytica. Biotechnology and Bioengineering, 114 (7), 1521-1530
22. Qiao K, Wasylenko T, Zhou K, Xu P and Stephanopoulos G. (2017) Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism. Nature Biotechnology, 35 (2), 173-177 MIT news.
21. Xu P, Qiao K, Ahn WK and Stephanopoulos G. (2016) Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals. Proceedings of the National Academy of Sciences, U.S.A., 113 (39), 10848-10853. Highlighted by Nature and Highlighted by DOE Office of Science.
20. Xu P, Rizzoni EA, Sul SY and Stephanopoulos G. (2016) Improving metabolic pathway efficiency by statistical model based multivariate regulatory metabolic engineering. ACS Synthetic Biology, 6 (1), 148-158.
19. Silverman, A, Qiao K, Xu P and Stephanopoulos GN. (2015) Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica. Applied Microbiology and Biotechnology. 100(8):3781-98. Link
18. Lim CG, Wong L, Bhan N, Dvora H, Xu P, Koffas M. (2015) Development of a recombinant Escherichia coli strain for overproduction of the plant pigment anthocyanin. Applied and Environmental Microbiology. 81(18):6276-84. Link
17. Trantas EA, Koffas MA, Xu P and Ververidis F. (2015) Biotechnology of flavonoids: Metabolic engineering with commercial applications when plants produce not enough or at all. Frontiers in Plant Science, 6:7.
16. Bhan N, Li L, Cai C, Xu P, Linhardt R and Koffas M. (2015) Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase. Protein Science, 24: 167-173.
15. Xu P, Li L, Zhang F, Stephanopoulos GN and Koffas MA. (2014) Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proceedings of the National Academy of Sciences, U.S.A., 111(31):11299-304. Highlighted as cover article on RPI news release.
14. Xu P, Wang W, Li L, Bhan N, Zhang F and Koffas MA. (2014) Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in E. coli. ACS Chemical Biology, 9(2): 451-458.
13. Wang W, Englaender J, Xu P, Linhardt RJ, Koffas MA. (2013) Expression of low endotoxin 3-O-sulfotransferase in B. subtilis and B. megaterium. Applied Biochemistry and Biotechnology, 171(4): 954-962.
12. Xu P, Gu Q; Wang W, Wong L, Bower A, Collins CH and Koffas MA. (2013) Modular optimization of multi-gene pathway for fatty acids production in E. coli. Nature Communications, 4: 1409.
11. Xu P, Bhan N and Koffas MA. (2013) Engineering plant metabolism into microbes: from systems biology to synthetic biology. Current Opinion in Biotechnology. 24(2): 291-299.
10. Bhan N, Xu P and Koffas MA. (2013) Pathway and protein engineering approaches to produce novel and commodity small molecules. Current Opinion in Biotechnology, 24(6): 1137-1143.
9. Bhan N, Xu P, Khalidi O and Koffas MA. (2013) Redirecting carbon flux into Malonyl-CoA to improve Resveratrol titers: Proof of concept for genetic interventions predicted by OptForce computational framework. Chemical Engineering Science, 103: 109-114.
8. Xu P and Koffas MA. (2013) Assembly of multi-gene pathways and combinatorial pathway libraries through ePathBrick vectors. Methods in Molecular Biology: Synthetic Biology. 1073:107-29.
7. Xu P, Vansiri A, Bhan N and Koffas MA. (2012) ePathBrick: A synthetic biology platform for engineering metabolic pathways in E. coli. ACS Synthetic Biology, 1(7):256–266.
6. Xu P, Ranganathan S, Fowler Z, Maranas CD and Koffas MA. (2011) Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. Metabolic Engineering, 13(5): 578-587.
5. Zhang L, Ding Z, Xu P et al. (2011) Methyl lucidenate F isolated from the ethanol-soluble-acidic components of G. lucidum is a novel tyrosinase inhibitor. Biotechnology and Bioprocess Engineering, 16(3): 457-461.
4. Xu P and Koffas MA. (2010) Metabolic engineering of E. coli for biofuel production, Biofuels, 1(3): 493-504.
3. Zhang T, Xu P et al. (2009) Identification of biological wort turbidity caused by microbial contamination of Gairdner barley. Journal of the American Society of Brewing Chemists, 67(1): 33-37.
2. Xu P, Ding Z, Qian Z, Zhang K and Zhao C. (2008) Improved production of mycelial biomass and ganoderic acid by submerged culture of G. lucidum SB97 using complex media. Enzyme and Microbial Technology, 42(4): 325-331.
1. Xu P, Qian Z, Zhao CX. (2008) Kinetic analysis of exo-polysaccharide and ganoderic acid production by submerged culture of Ganoderma lucidum. Chinese Journal of Applied & Environmental Biology, 14(4): 562-565. 1. Xu P*.